Advice

following a full submission:

rivaroxaban (Xarelto®) is accepted for use within NHS Scotland.

Indication under review: treatment of pulmonary embolism (PE), and prevention of recurrent deep vein thrombosis (DVT) and PE in adults.

Rivaroxaban was non-inferior to a regimen including a low molecular weight heparin and a vitamin K antagonist for the treatment of PE and the prevention of recurrence of DVT or PE.  Duration of treatment was 3, 6 or 12 months at the discretion of the treating physician.

Experience with rivaroxaban in this indication for more than 12 months is limited therefore the cost-effectiveness of indefinite treatment has not been demonstrated.

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Medicine details

Medicine name:
rivaroxaban (Xarelto)
SMC ID:
852/13
Indication:
Treatment of pulmonary embolism (PE), and prevention of recurrent deep vein thrombosis (DVT) and PE in adults.
Pharmaceutical company
Bayer plc/Bayer Schering Pharma
BNF chapter
Cardiovascular system
Submission type
Full
Status
Accepted
Date advice published
11 March 2013