Advice

Recommended for general use within NHS Scotland.
 
Indication Under Review:

primary hypercholesterolaemia (type IIa including heterozygous familial hypercholesterolaemia) or mixed dyslipidaemia (type IIb) as an adjunct to diet, when response to diet and exercise is inadequate.

homozygous familial hypercholesterolaemia, either alone or as an adjunct to diet and other lipid-lowering treatments (e.g. LDL apheresis).
 
Recommendation
 
Rosuvastatin is a new HMG-CoA reductase inhibitor, with costs and efficacy in reducing low-density-lipoprotein-cholesterol (LDL-C) comparable to other statins.  Its current licenced indications are more limited than some other statins.

Download detailed advice41KB (PDF)

Download

Medicine details

Medicine name:
rosuvastatin (Crestor)
SMC ID:
45/03
Indication:
Primary hypercholesterolaemia or mixed dyslipidaemia
Pharmaceutical company
AstraZeneca UK Ltd
BNF chapter
Cardiovascular system
Submission type
Full
Status
Accepted
Date advice published
09 May 2003