Advice

Following a resubmission.

Rotigotine (Neupro®) is accepted for use within NHS Scotland for the treatment of the signs and symptoms of early-stage idiopathic Parkinson’s disease as monotherapy (i.e. without levodopa).

Rotigotine was superior to placebo in two randomised controlled trials. However, in one active comparator study it was less effective than a non-ergolinic dopamine agonist comparator. Rotigotine transdermal patch offers an alternative non-ergolinic dopamine agonist at a lower cost in a formulation that does not have to be taken by mouth.

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Medicine details

Medicine name:
rotigotine 2mg/24 hours, 4mg/24 hours, 6mg/24 hours, 8mg/24 hours transdermal patch (Neupro)
SMC ID:
289/06
Indication:
Early-stage Parkinson's disease
Pharmaceutical company
Schwarz Pharma Ltd
BNF chapter
Central nervous system
Submission type
Resubmission
Status
Accepted
Date advice published
09 July 2007