Advice

in the absence of a submission from the holder of the marketing authorisation:

ruxolitinib (Jakavi®) is not recommended for use within NHSScotland.

Indication under review: for the treatment of:

  • patients aged 12 years and older with acute graft versus host disease who have inadequate response to corticosteroids
  • patients aged 12 years and older with chronic graft versus host disease who have inadequate response to corticosteroids

The holder of the marketing authorisation has not made a submission to SMC regarding this product in this indication. As a result we cannot recommend its use within NHSScotland.

Download detailed advice620KB (PDF)

Download

Medicine details

Medicine name:
ruxolitinib (Jakavi®)
SMC ID:
SMC2498
Indication:

for the treatment of:

  • patients aged 12 years and older with acute graft versus host disease who have inadequate response to corticosteroids
  • patients aged 12 years and older with chronic graft versus host disease who have inadequate response to corticosteroids
Pharmaceutical company
Novartis Pharmaceuticals UK Ltd
BNF chapter
Malignant disease and immunosuppression
Submission type
Non submission
Status
Not recommended
Date advice published
13 June 2022