in the absence of a submission from the holder of the marketing authorisation:
setmelanotide (Imcivree®) is not recommended for use within NHSScotland.
Indication under review: Treatment of obesity and the control of hunger associated with genetically confirmed loss-of-function biallelic pro-opiomelanocortin (POMC), including PCSK1, deficiency or biallelic leptin receptor (LEPR) deficiency in adults and children 6 years of age and above.
The holder of the marketing authorisation has not made a submission to SMC regarding this product in this indication. As a result we cannot recommend its use within NHSScotland.
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Medicine details
- Medicine name:
- setmelanotide (Imcivree)
- SMC ID:
- SMC2565
- Indication:
Treatment of obesity and the control of hunger associated with genetically confirmed loss-of-function biallelic pro-opiomelanocortin (POMC), including PCSK1, deficiency or biallelic leptin receptor (LEPR) deficiency in adults and children 6 years of age and above.
- Pharmaceutical company
- Rhythm Pharmaceuticals
- BNF chapter
- Nutrition and blood
- Submission type
- Non submission
- Status
- Not recommended
- Date advice published
- 16 January 2023