Advice

Following a full submission.

Sildenafil citrate (Revatio) is accepted for restricted use within NHS Scotland for the treatment of patients with pulmonary arterial hypertension classified as WHO functional class III, to improve exercise capacity.

This is an orphan indication for sildenafil with limited clinical evidence from short-term clinical trials. It is restricted to initiation by specialists working in the Scottish Pulmonary Vascular Unit and by physicians experienced in the management of pulmonary vascular disease.

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Medicine details

Medicine name:
Sildenafil citrate 20mg tablets (Revatio®)
SMC ID:
235/06
Indication:
Pulmonary arterial hypertension
Pharmaceutical company
Pfizer Ltd
BNF chapter
Cardiovascular system
Submission type
Full
Status
Restricted
Date advice published
13 February 2006