Advice

following a full submission:

solriamfetol (Sunosi®) is not recommended for use within NHSScotland.

Indication under review: to improve wakefulness and reduce excessive daytime sleepiness (EDS) in adult patients with obstructive sleep apnoea (OSA) whose EDS has not been satisfactorily treated by primary OSA therapy, such as continuous positive airway pressure (CPAP).

Solriamfetol, compared with placebo, reduced EDS in adults with OSA who were currently using or had previously tried a primary OSA therapy.

The submitting company did not present a sufficiently robust clinical and economic analysis to gain acceptance by SMC.

Medicine details

Medicine name:
solriamfetol (Sunosi)
SMC ID:
SMC2419
Indication:

To improve wakefulness and reduce excessive daytime sleepiness (EDS) in adult patients with obstructive sleep apnoea (OSA) whose EDS has not been satisfactorily treated by primary OSA therapy, such as continuous positive airway pressure (CPAP).

Pharmaceutical company
Jazz Pharmaceuticals
BNF chapter
Central nervous system
Submission type
Full
Status
Not recommended
Date advice published
07 March 2022