Advice

following a full submission: 

telaprevir (Incivo®) is accepted for use within NHS Scotland. 

Indication under review: in combination with peginterferon alfa and ribavirin, for the treatment of genotype 1 chronic hepatitis C in adult patients with compensated liver disease (including cirrhosis) who are treatment-naïve. 

In the pivotal phase III randomised study, addition of telaprevir to current standard therapy in treatment-naïve patients with genotype 1 chronic hepatitis C virus, significantly increased the proportion of patients who achieved a sustained virologic response, even in patients treated for a shorter overall duration using response-guided therapy.

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Medicine details

Medicine name:
telaprevir (Incivo) Naive
SMC ID:
743/11
Indication:
In combination with peginterferon alfa and ribavirin (PR), for the treatment of genotype 1 chronic hepatitis C in adult patients with compensated liver disease (including cirrhosis): who are treatment naive
Pharmaceutical company
Janssen-Cilag Ltd
BNF chapter
Infections
Submission type
Full
Status
Accepted
Date advice published
12 December 2011