Advice

following a full submission

tinzaparin (Innohep Syringe®) is accepted for use within NHS Scotland.

Indication under review: Patients with solid tumours: Extended treatment of symptomatic venous thrombo-embolism (VTE) and prevention of its recurrence.

In patients with cancer and VTE, tinzaparin was associated with rates of VTE recurrence that were not significantly different from those with a vitamin K antagonist (VKA).  In a large study it was not significantly different from a VKA for a composite outcome that included symptomatic deep vein thrombosis (DVT), non-fatal and fatal pulmonary embolism (PE), incidental DVT and PE.

This advice takes account of the benefits of a Patient Access Scheme (PAS) that improves the cost-effectiveness of tinzaparin.  This advice is contingent upon the continuing availability of the patient access scheme in NHS Scotland or a list price that is equivalent or lower.

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Medicine details

Medicine name:
tinzaparin sodium (Innohep)
SMC ID:
1061/15
Indication:
Patients with solid tumours: Extended treatment of symptomatic venous thrombo-embolism (VTE) and prevention of its recurrence.
Pharmaceutical company
LEO Pharmaceuticals
BNF chapter
Cardiovascular system
Submission type
Full
Status
Accepted
Date advice published
13 July 2015