Advice

in the absence of a submission from the holder of the marketing authorisation:

vildagliptin/metformin hydrochloride (Eucreas®) is not recommended for use within NHS Scotland.

Indication under review: Treatment of type 2 diabetes mellitus:

  • in combination with a sulphonylurea (i.e. triple combination therapy) as an adjunct to diet and exercise in patients inadequately controlled with metformin and a sulphonylurea
     
  • in triple combination therapy with insulin as an adjunct to diet and exercise to improve glycaemic control in patients when insulin at a stable dose and metformin alone do not provide adequate glycaemic control

The holder of the marketing authorisation has not made a submission to SMC regarding this product in these indications.  As a result we cannot recommend its use within NHSScotland.

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Medicine details

Medicine name:
vildagliptin / metformin hydrochloride (Eucreas®)
SMC ID:
874/13
Indication:
Treatment of type 2 diabetes mellitus: in combination with a sulphonylurea (i.e. triple combination therapy) as an adjunct to diet and exercise in patients inadequately controlled with metformin and a sulphonylurea - in triple combination therapy with insulin as an adjunct to diet and exercise to improve glycaemic control in patients when insulin at a stable dose and metformin alone do not provide adequate glycaemic control.
Pharmaceutical company
Novartis Pharmaceuticals UK Ltd
BNF chapter
Endocrine system
Submission type
Non submission
Status
Not recommended
Date advice published
13 May 2013