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clofarabine, 1mg/ml concentrate for solution for infusion (Evoltra)

Acute lymphoblastic leukaemia

dasatinib (Sprycel)

Philadelphia chromosome positive (PH+) actue lymphoblastic leukaemia

nelarabine (Atriance)

For the treatment of patients with T-cell acute lymphoblastic leukaemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL)

mercaptopurine (Xaluprine)

For the treatment of acute lymphoblastic leukaemia (ALL) in adults, adolescents and children.

asparaginase (Spectrila)

Component of antineoplastic combination therapy for the treatment of acute lymphoblastic leukaemia in paediatric patients from birth to 18 years and adult patients.

pegaspargase (Oncaspar)

As a component of antineoplastic combination therapy in acute lymphoblastic leukaemia (ALL) in paediatric patients from birth to 18 years, and adult patients.

imatinib (Glivec)

Treatment of paediatric patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukaemia (Ph+ ALL) integrated with chemotherapy.

imatinib (Glivec)

for the treatment of adult patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukaemia (PH + ALL) in combination with chemotherapy

imatinib (Glivec)

for the treatment of adult patients with relapsed or refractory Philadelphia chromosome positive acute lymphoblastic leukaemia (Ph+ ALL) as monotherapy

dasatinib (Sprycel)

The treatment of paediatric patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukaemia in combination with chemotherapy.

blinatumomab (Blincyto)

the treatment of adults with Philadelphia chromosome negative relapsed or refractory B-precursor acute lymphoblastic leukaemia (ALL).

brexucabtagene autoleucel (Tecartus)

Treatment of adult patients 26 years of age and above with relapsed or refractory B-cell precursor acute lymphoblastic leukaemia (ALL).

inotuzumab ozogamicin (Besponsa)

As monotherapy for the treatment of adults with relapsed or refractory CD22-positive B cell precursor acute lymphoblastic leukaemia. Adult patients with Philadelphia chromosome positive relapsed or refractory B cell precursor acute lymphoblastic leukaemia should have failed treated with at least 1 tyrosine kinase inhibitor.

tisagenlecleucel (Kymriah)

Treatment of paediatric and young adult patients up to 25 years with B-cell acute lymphoblastic leukaemia (ALL) that is refractory, in relapse post-transplant or in second or later relapse

blinatumomab (Blincyto®)

As monotherapy for the treatment of adults with CD19 positive relapsed or refractory B-precursor acute lymphoblastic leukaemia (ALL). Patients with Philadelphia chromosome positive B-precursor ALL should have failed treatment with at least 2 tyrosine kinase inhibitors (TKIs) and have no alternative treatment options.