Advice

following a full submission:

durvalumab (Imfinzi®) is accepted for use within NHSScotland.

Indication under review: As monotherapy for the treatment of adults with limited-stage small cell lung cancer (LS-SCLC) whose disease has not progressed following platinum-based chemoradiation therapy.

In a randomised, double blind phase III study, durvalumab significantly improved progression free and overall survival compared with placebo in patients with LS SCLC who had not progressed following concurrent chemoradiotherapy.

This advice applies only in the context of an approved NHSScotland Patient Access Scheme (PAS) arrangement delivering the cost-effectiveness results upon which the decision was based, or a PAS/ list price that is equivalent or lower.

Medicine details

Medicine name:
durvalumab (Imfinzi)
SMC ID:
SMC2818
Indication:

Treatment of adults with limited-stage small-cell lung cancer (LS-SCLC) whose disease has not progressed following platinum-based chemoradiation therapy (CRT).

Pharmaceutical company
AstraZeneca UK Ltd
BNF chapter
Malignant disease and immunosuppression
Submission type
Full
Status
Accepted
Date advice published
11 May 2026