Advice

in the absence of a submission from the holder of the marketing authorisation:

gefapixant (Lyfnua®) is not recommended for use within NHSScotland.

Indication under review: in adults for the treatment of refractory or unexplained chronic cough.

The holder of the marketing authorisation has not made a submission to SMC regarding this product in this indication. As a result, we cannot recommend its use within NHSScotland.

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Medicine details

Medicine name:
gefapixant (Lyfnua)
SMC ID:
SMC2926
Indication:

In adults for the treatment of refractory or unexplained chronic cough.

Pharmaceutical company
Merck Sharp & Dohme Ltd
BNF chapter
Respiratory system
Submission type
Non submission
Status
Not recommended
Date advice published
11 May 2026