Advice

Following a full submission

Metformin (Glucophage SR®) is not recommended for use within NHS Scotland for the treatment of type 2 diabetes mellitus in adults, particularly in overweight patients, when dietary management and exercise alone do not result in adequate glycaemic control.

Metformin (Glucophage SR) did not demonstrate any benefits in efficacy or side effect profile over the immediate release metformin and is considerably more expensive.

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Medicine details

Medicine name:
Metformin hydrochloride (Glucophage SR®)
SMC ID:
148/04
Indication:
Type-2 diabetes mellitus
Pharmaceutical company
Merck Serono Ltd
BNF chapter
Endocrine system
Submission type
Full
Status
Not recommended
Date advice published
07 March 2005